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Xlear Nasal Wash contains purified water, xylitol, saline, and grapefruit seed extract as a preservative. Xylitol is the key ingredient that makes Xlear Nasal Wash so revolutionary and effective. The most important part of using Xlear is to use it regularly. Even when a person does not have symptoms of congestion, harmful bacteria can be living in the nose. Washing the nose regularly is just as helpful as washing ones hands regularly.